After Bobby discovers Crowley has no intentions of returning Bobby’s soul, the hunter takes matters into his own hands. He calls on Sam and Dean for help after he unearths one of Crowley’s deepest secrets. Meanwhile, Sam and Dean learn what Bobby does all day when they are not around.

Sam and Dean seek Castiel’s help when they investigate a case of police officers who seem to have been killed by Egyptian plagues.

Sam investigates a case about missing babies whose parents are being murdered. At one of the crime scenes, he discovers a baby that was left behind and calls Dean for help. Reluctant to leave Lisa and Ben, Dean finally agrees to meet Sam and surprises his brother with how parental he has become. The brothers take the baby to Samuel, who decides to raise it as a hunter, which infuriates Dean. However, before they can decide the...

Sam is mysteriously released from Hell and seeks out his brother, trying to have a normal life. Together the brothers must join forces with their maternal grandfather, Samuel, and begin the fight anew.